Lami cream®
treatment foe skin fungi infection
  • Terbinafine is a synthetic allylamine, which has a broad spectrum antifungal activity. At low concentration Terbinafine is fungicidal against dermatophytes, mould and certain dimorphic fungi. The activity against yeasts is fungicidal or fungistatic, depending on the species.
  • Terbinafine interferes specifically with fungal sterol biosynthesis at early step.This leads to a deficiency in ergosterol and to an intracellular accumulation of squalene, resulting in fungalcell death.
  • Terbinafine acts by inhibition of squalene epoxidase in the fungal cell membrane . The enzyme squalene epoxidase is not linked to the cytochrome P450 system ,Terbinafine dose not influence the metabolism of hormones or other drugs. When given orally the drug concentrates in skin, hair and nails at levels associated with fungicidal activity.
  • When given topically, the drug has a rapid onset of action and can be effective with short treatment duration .

Each gram  of Lami cream® contains:

  • Terbinafine hydrochloride          10 mg 
  • Infections of the skin caused by dermatophytes such as Trichophyton(eg:T.rubrum ,T.violaceum T.mentagrophytes, T.verrucosum).Microsporum canis and Epidermophyton floccosum. Yeast infections of the skin , principally those caused by the genus Candida (e.g.Candida albicans) ,Pityriasia (tinea) 
  • Hypersensitivity to Terbinafine.
  • If the treatment is topical, the small amount of Terbinafine absorbed by the skin is unlikely to cause damage for the fetus and the infant.
  • Redness, itching or stinging occasionally occur at the site of application for this reason these harmless reaction must be distinguished from allergic reactions which are rare but require discontinuation.
  • Lami cream® can be applied once or twice daily. Cleanse and dry the affected areas thoroughly before treating with Lami cream® .
  • Apply cream to the affected skin and surrounding area in a thin layer and gently rub in.
  • The case of interiginous infection (submammary, interdigital, intergluteal, inguinal) the application may be covered with gauze especially at night.
  • Lami cream® is for external use only, contact with eyes should be avoided.
  • Lami® cream : tube of 15 g cream .
  • Store below 25°C.