Ibufinal 100
Ibufinal 100
ANALGESICS/ANTIPYRETICS/ANTI-INFLAMMATORY DRUG
Indication
Ibufinal® is used in:
- Management of mild to moderate pain and inflammation in conditions such as headache including migraine, postoperative pain and dental pain.
- Musculoskeletal and joint disorder such as ankylosing spondylitis and juvenile idiopathic arthritis.
- Periarticular disorders such as tenosynovitis and bursitis.
- Soft-tissue disorders such as sprains and strains.
- It is also used to reduce fever.
Composition
Each 5 ml of Ibufinal® oral suspension contains:
- Ibuprofen 100 mg.
Dosage
¤ Administer with or after food or milk to reduce the gastrointestinal effects.
¤ Daily doses of Ibufinal® oral suspension in terms of age:
- 6- 12 months: 2.5ml 3 times daily.
- 1 -2 years: 2.5ml 3- 4 times daily.
- 2- 7 years: 5 ml 3 -4 times daily.
- 7 years & over: 10 ml 3 -4 times daily.
¤ Daily doses in terms of body weight (for children and infants weighing more than 7 kg):
- Juvenile Rheumatoid Arthritis: 30- 40 mg/kg daily in 3 -4 divided doses
- Antipyretic, Analgesic: 20- 30 mg/kg daily in divided doses.
¤ Adults: 1200- 1800 mg daily does.
- Ibuprofen is a propionic acid derivative with anti-inflammatory, analgesic and antipyretic properties.
- It has fewer side effects than other NSAIDS.
- Ibuprofen is non-steroidal anti-inflammatory agent that inhibits prostaglandin synthesis by decreasing the activity of the enzyme cyclo-oxygenase, which results in decreased formation of prostaglandin precursors.
Each 5 ml of Ibufinal® oral suspension contains:
- Ibuprofen 100 mg.
Ibufinal® is used in:
- Management of mild to moderate pain and inflammation in conditions such as headache including migraine, postoperative pain and dental pain.
- Musculoskeletal and joint disorder such as ankylosing spondylitis and juvenile idiopathic arthritis.
- Periarticular disorders such as tenosynovitis and bursitis.
- Soft-tissue disorders such as sprains and strains.
- It is also used to reduce fever.
Ibufinal® is contraindicated in:
- Patients with hypersensitivity to ibuprofen, aspirin, or other NSAIDs.
- Patients with "aspirin triad" (bronchial asthma, aspirin intolerance, rhinitis).
- Patients with active peptic ulcer, GI bleeding.
- In coagulation defects.
- Ibuprofen may reduce the cardio-protective effect of aspirin.
- Ibuprofen can reduce the natriuretic effect of furosemide and thiazides in some patients.
- There may be an increased risk of hyperkalaemia with ACE inhibitors and potassium-sparing diuretics.
- Enhancement of the effects of oral anticoagulants.
- Increased plasma concentrations (toxicity) of Lithium, Methotrexate, and cardiac glycosides.
- The antihypertensive effects of ACE inhibitors, Beta blockers, and diuretics may be reduced.
- Use of more than one NSAID together should be avoided because of the increased risk of adverse effects.
- Ibuprofen is usually well tolerated. some minor side effects have occasionally been reported such as skin rashes, dizziness, nausea, heart burn or abdominal discomfort.
- Rarely, asymptomatic thrombocytopenia and gastrointestinal bleeding and ulceration have been reported.
¤ Administer with or after food or milk to reduce the gastrointestinal effects.
¤ Daily doses of Ibufinal® oral suspension in terms of age:
- 6- 12 months: 2.5ml 3 times daily.
- 1 -2 years: 2.5ml 3- 4 times daily.
- 2- 7 years: 5 ml 3 -4 times daily.
- 7 years & over: 10 ml 3 -4 times daily.
¤ Daily doses in terms of body weight (for children and infants weighing more than 7 kg):
- Juvenile Rheumatoid Arthritis: 30- 40 mg/kg daily in 3 -4 divided doses
- Antipyretic, Analgesic: 20- 30 mg/kg daily in divided doses.
¤ Adults: 1200- 1800 mg daily does.
- Ibufinal® should be used with caution in patients with renal, cardiac, or hepatic impairment, or those receiving anticoagulants (Use lowest dose for the shortest period possible).
- CNS adverse effects such as confusion, agitation, & hallucination are generally seen in overdose situations.
- Ibufinal® is preferable to avoid in patients with current or previous GI ulceration or bleeding.
- Ibufinal® : Bottle of 60 ml or 100 ml Oral Suspension.
- Store at temperature not exceeding 25ºC.