Nebivel® 5mg
Antihypertensive/Antianginal
  • Nebivel® belongs to a group of drugs called “beta blockers.”
  • It makes your heart beat more slowly and less forcefully.
  • It lowers your blood pressure by relaxing your blood vessels so that your blood flows more easily.
  • This medicine does not cure your disease but helps to control it. 

Each film coated tablet of Nebivel® contains:

  • Nebivolol        2.5 mg
  • Nebivolol         5 mg
  • Nebivolol        10 mg
  • Nebivolol         20 mg (as Nebivolol Hcl).
  • Nebivel® prevents increased heart rate, controls heart pumping strength.
  • It also exerts a dilating action on blood vessels, which contributes as well to lower blood pressure.
  • Nebivel® is also used to treat mild and moderate chronic heart failure in patients aged 70 or over, in addition to other therapies.

do not take this medcine if you:

  • Are allergic to nebivolol or any of the other ingredients in Nebivel® . 
  • Have heart failure and you notice that your symptoms are getting worse. For example you feel more tired, are out of breath more often, or have   
    swelling of the ankles.
  • Have severe heart damage and your heart is not able to pump enough blood to meet your body’s needs.
  • Have a slow or irregular heart beat.
  • Have an abnormal heart rate or rhythm.
  • Have a problem with your heart’s electrical conduction (that causes you to have chest pain, difficulty breathing, nausea, fatigue and fainting).
  • Have severe liver disease.
  • Have serious problems with blood flow in your feet and legs (peripheral artery disease).

Have one of the following rare hereditary diseases:

  • Galactose intolerance.
  • Lapp lactase deficiency.
  • Glucose Galactose malabsorption.
  • You are 18 years and younger.

the following drugs may ineract with Nebivel® :   

  • Drugs used for lowering blood pressure (such as ACE inhibitors (such as lisinopril), Calcium channel blockers (such as verapamil and diltiazem) and Clonidine.
  • Drugs used to treat depression and mood disorders (such as fluoxetine, paroxetine, and venlafaxine)
  • Anesthetic drugs used during surgery (such as ether and cyclopropane)
  • Drugs used to treat diabetes such as insulin and oral medicines.
  • Drugs used to treat heartburn and ulcers (such as cimetidine)
  • Antidiuretic drugs used to reduce the fluid build-up in your body (such ashydrochlorothiazide, furosemide and spironolactone)
  • Sildenafil, a drug used to treat erectile dysfunction
  • Drugs used to treat HIV/AIDS
  • Drugs used to treat heart rhythm disorders (such as amiodarone، disopyramide، flecainide and digoxin)
  • Dexamethasone, a steroid drug used to treat inflammation
  • Rifampin used to treat tuberculosis
  • Fingolimod, a medicine used to treat multiple sclerosis
  • Nebivel® should not be used during pregnancy, unless clearly necessary.
  • It is not recommended for use while breast-feeding.
  • If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby,ask your doctor or pharmacist for advice before taking this medicine.

¤ These are not all the possible side effects you may feel when you are taking Nebivel®.If you experience any side effects not listed here, contact your healthcare professional.

Side effects may include:

  • Cough
  • Diarrhea
  • Dizziness
  • Dry mouth
  • Headache
  • Joint and back pain
  • Nausea
  • Stuffy nose and colds
  • Tiredness
  • Trouble sleeping
  • Serious side effects:

Common:

  • Bradycardia: decreased heart rate that causes you to be dizzy or faint. 
  • Chest pain. 

Uncommon:

  • Allergic reactions: rash, swelling of the lips, face or neck, difficulty breathing or speaking.
  • Heart attack: chest pain, squeezing or pressure, fast or irregular heartbeat,nausea, trouble breathing, sweating.
  • Heart conduction disorders: feeling lightheaded, dizzy, or passing out.
  • Hypotension (low blood pressure):dizziness or lightheadedness leading to fainting can occur when changing positions, for example from lying down to standing up.
  • Irregular heart beats or heart palpitations (skipped beats).
  • Leg swelling from fluid retention .
  • Memory problem
  • Shortness of breath 
  • Skin reactions: rash 
  • Vision problems
  • Always take this medicine exactly as your doctor has told you.
  • Check with your doctor or pharmacist if you are not sure.
  • Nebivel® may be taken before, during or after the meal, but, alternatively, you can take it independently of meals,the tablet is best taken with some water.

Usual Adult dose:

  • Starting daily dose: 5 mg once a day
  • Maximum daily dose: 20 mg once a day

Your doctor may:

  • start you on a different dose or change your dose over time depending on how Nebivel® works for you.
  • add another medicine like a diuretic (water pill) or an ACE inhibitor for you to take along with Nebivel® to treat your high blood pressure.
  • Do not stop taking Nebivel® or change your dose without consulting your doctor because this can be dangerous.
  • Have asthma or other lung problems (like bronchitis or emphysema).
  • Have a history of heart problems.
  • Have a history of fainting.
  • Have diabetes and take medicine to control your blood sugar or have low blood sugar (hypoglycemia).
  • Have a condition called pheochromocytoma (a tumour of the adrenal gland).
  • Have thyroid problems.
  • Have liver or kidney problems.
  • Have had allergic reactions or have allergies.
  • Are scheduled for surgery and will be given an anesthetic.
  • Develop a skin rash while taking Nebivel®.

 Other warnings you should know about:

  • Do not stop taking Nebivel® suddenly. This could cause chest pain or a heart attack. If your doctor decides that you should stop taking Nebivel®, your dose may be reduced so that you need to use less and less before you stop the medication completely.

Children and adolescents:

  • Because of the lack of data on the use of the product in children and adolescents, Nebivel® is not recommended for use in them.
  • Nebivel® film coated tablets  (Blister of 10 tablets, pack of 2 blisters).
  • Store at a temperature below 25 °C.
  • Protect from light