Each Suppository  of  Dicloban® 25 contains:

• Diclofenac sodium     25 mg

Each Suppository  of  Dicloban® 12.5 contains:

• Diclofenac sodium     12.5 mg

Dicloban® is used in:

• Inflammatory and degenerative forms of rheumatism: ( rheumatoid arthritis, ankylosing spondylitis, osteoarthritis and spondylarthritis). 
• Painful syndromes of the vertebral column. 
• Non-articular rheumatism. 
• Post-traumatic and postoperative pain, inflammation, and swelling. 
• Painful and inflammatory conditions in gynaecology, e. g. ( primary dysmenorrhea or adnexitis) .    
• Soft tissue injuries: ( sprain and strain ) . 
• Acute infectious diseases, especially of the ear, nose and throat. 
• Dental pain, renal and biliary colics.
• Acute gout and Juvenile rheumatoid arthritis.

 Dicloban® should not be given to:

• Patients with hypersensitivity to Diclofenac sodium; 
• Patients with peptic ulcer and to patients who have experienced asthma, urticaria, or other allergic-type reactions caused by Aspirin or other NSAID. 

• Dicloban® may reduce the efficacy of diuretics. 
• Concomitant treatment with a potassium-sparing diuretic may be associated with increased serum potassium levels, which should therefore be monitored frequently. 
• Patients taking Dicloban® and are also receiving (Digoxin, Methotrexate, Cyclosporin or Lithium) should be observed for potential development of the specific toxicities of these drugs. 
• Concomitant administration of other systemic NSAIDs or Glucocorticoids may increase the occurrence of side effects. 
• Cholestyramine appears to reduce the bioavailability of Diclofenac when the two drugs are given together; Colestipol produces a similar action but smaller effect. 

• Owing to the possibility of uterine inertia and/or premature closure of the ductus arteriosus, Dicloban® should not be used in the third trimester. 
• Dicloban® passes into breast milk, but in quantities so small to be harmful to a breast-fed infant. 

*is generally well tolerated.

*The most common side effects include:-

• gastro-intestinal disturbances
• headache
• dizziness
• fluid retention
• liver function disorders
• rash and pruritis have been reported. 

* The dose should be adjusted to the patient’s response, tolerance and severity of symptoms. 

* Dicloban® capsules or tablets should be swallowed whole with plenty of  liquid preferably during or  after meals. 

Adults:

-The recommended daily dosage is 75–150 mg as the following:

• One capsule of Dicloban® SR 100 per day during long term treatment. 
• Or 1–3 enteric coated tablets of Dicloban® 25 or 50 daily in 2–3 divided doses.
• In primary dysmenorrhoea the daily dosage should be individually adjusted and generally 50–150 mg.

Children:

-The initial dose for children aged 6 years and over:

• 2–3 mg/kg body weight / day, in 2–3 divided doses.
• The dose range is between 0.5-2 mg/Kg body weight daily, according to the severity of the case.
• In case of juvenile rheumatoid arthritis, the dose can be increased to 3 mg/Kg body weight daily on 2-3 divided doses.
• Dicloban® should not be given to children under 12 months of age.
• Or as directed by the physician.

 Dicloban® should be used with caution:

• In patients with impaired hepatic or renal function
• In patients with history of cardiovascular diseases and peptic ulcer.

Dicloban® 25 mg and 12.5 mg Suppository : 

• (Blisters of 5 Suppository  , Packs of one blisters.)

• Store in a dry place at a temperature below 25°C.
• Protect from moisture and light.