Vinor®
Vinor®
Antinauseant & Antiemetic
Indication
- Nausea & vomiting of pregnancy.
- Antiemetic agent for emesis induced by drug, post anesthetic vomiting, postoperative, and motion sickness.
- For management of vertigo caused by Meniere’s disease and other vestibular disorders .
Composition
Each capsule of Vinor® contains:
- Meclozine hydrochloride 25 mg
- Pyridoxine hydrochloride (Vit. B6) 50 mg
Each Tablet of Vinor® contains:
- Meclozine hydrochloride 25 mg
- Pyridoxine hydrochloride (Vit. B6) 50 mg
Dosage
- In severe nausea and vomiting of pregnancy: One dose of Vinor® at bedtime and one doses in the morning.
- For prevention of motion sickness: One to two dose of Vinor® taken 1 hour before traveling, to be repeated every 24 hours as needed.
- As antivertigo: One to four dose of Vinor® as needed in divided doses.
- For postoperative vomiting: Two dose of Vinor® four
- Vinor® is antiemetic and antinauseant formulation of meclozine hydrochloride and pyridoxine hydrochlorid.
- It diminishes vestibular stimulation & depresses labyrinthine function. It acts also on the medullary chemoreceptor trigger zone to exert its antiemetic, antimotion sickness & antivertigo effects.
- Meclozine hydrochloride has a sedating antihistamine with antimuscarinic and moderate sedative properties so it is used in the prevention and treatment of nausea and vomiting associated with a variety of conditions .
- In addition, the presence of pyridoxine in the formulation makes it beneficial in pregnancy due to the conversion in the erythrocytes to pyridoxal phosphate, the active form of the vitamin B6, which acts as a coenzyme for various metabolic functions affecting protein, carbohydrates and lipid utilization.
Each capsule of Vinor® contains:
- Meclozine hydrochloride 25 mg
- Pyridoxine hydrochloride (Vit. B6) 50 mg
Each Tablet of Vinor® contains:
- Meclozine hydrochloride 25 mg
- Pyridoxine hydrochloride (Vit. B6) 50 mg
- Nausea & vomiting of pregnancy.
- Antiemetic agent for emesis induced by drug, post anesthetic vomiting, postoperative, and motion sickness.
- For management of vertigo caused by Meniere’s disease and other vestibular disorders .
- Contraindicated in patients on levodopa therapy (Pyridoxine decreases efficacy of levodopa.)
- A previous hypersensitivity to this product.
- Vinor® may enhance the sedative effects of CNS depressants including( alcohol, barbiturates, hypnotics, opioid, analgesics, anxiolytic, sedatives, and antipsychot-ics).
- Vinor® may suppress the cutaneous histamine response to allergen extracts and should be stopped several days before skin testing.
- Meclozine may be excreted in breast milk and it may be inhibit lactation due to its antimuscarinic action.
- Drowsiness, blurred vision and dryness of mouth, nose and throat.
- In severe nausea and vomiting of pregnancy: One dose of Vinor® at bedtime and one doses in the morning.
- For prevention of motion sickness: One to two dose of Vinor® taken 1 hour before traveling, to be repeated every 24 hours as needed.
- As antivertigo: One to four dose of Vinor® as needed in divided doses.
- For postoperative vomiting: Two dose of Vinor® four
- Drowsiness is a major problem with sedating antihistamines and those effected should not drive or operate machinery; alcohol should be avoided.
- Vinor® should be given with caution to patients with impaired liver function.
- Due to the potential anticholenergic action of meclozine hydrochloride, this drug should be used with caution in patients with asthma, glaucoma, or enlargement of the prostate gland.
- Vinor® Capsules :(Blister of 10 Capsules, Pack of Two blisters).
- Vinor® Tablets :(Blister of 10 tablets, Pack of Two blisters).
- Store in a dry place at a temperature between 15° C – 30° C