Indication
Lomefent® are indicated for the local treatment of :
- Trichomonas vaginalis .
- Vaginal infections sustained by mixed forms of Trichomonas vaginalis and candida albicans .
- Genital candidiasis (vulvovaginitis, colpitis, infectious fluor) .
Composition
Each ovule of Lomefent® vaginal ovule contains :
- Fenticonazole nitrate 600 mg Or 1000 mg
Each tube of Lomefent® vaginal Cream contains :
- Fenticonazole nitrate 2%
Dosage
Lomefent® 1000 mg vaginal ovule :
-Trichomonas or mixed ( trichomonas and candida albicans ) vaginal infections :
- One 1000 mg ovule followed by a second administration 24 hours later, when necessary .
-Candida albicans infections :
- One 1000 mg ovule followed by a second administration in the evening . Should the symptoms persist, a second administration may be repeated after three days .
Lomefent® 600 mg vaginal ovule:
- One 600 mg ovule at bedtime followed by a second administration 3 days later if symptoms persist.
* The ovules must be introduced deep into the vagina and pushed well up to the fornix .
Lomefent® vaginal Cream :
- One applicator full (5 g) is administered into the vagina morning and before going to bed for three days.
- The active component of Lomefent® is Fenticonazole nitrate that is an imidazole antifungal agent with antimicrobial activity against some gram-Positive bacteria and is therefore indicated in mycosis associated with bacterial super infections.
- Fenticonazole nitrate exerts fungistatic and fungicidal actions on dermatophytes (responsible for most mycotic skin infections) pathogenic yeasts, dimorphous fungi and moulds.
- Lomefent® is active, both in vitro and in vivo,against trichomonas vaginalis .
Each ovule of Lomefent® vaginal ovule contains :
- Fenticonazole nitrate 600 mg Or 1000 mg
Each tube of Lomefent® vaginal Cream contains :
- Fenticonazole nitrate 2%
Lomefent® are indicated for the local treatment of :
- Trichomonas vaginalis .
- Vaginal infections sustained by mixed forms of Trichomonas vaginalis and candida albicans .
- Genital candidiasis (vulvovaginitis, colpitis, infectious fluor) .
- Hypersensitivity to Fenticonazole nitrate .
- Due to the limited systemic availability after vaginal application, clinically relevant interactions occur very rarely.
- Contact should be avoided between latex products (such as contraceptive diaphragms, condoms) and Lomefent® , since intra vaginal preparations of fenticonazole may damage the latex .
Use during pregnancy :
- Although transcutaneous and vaginal absorption of Fenticonazole is very poor, use of the preparation is not recommended in pregnancy .
Use during lactation :
- It is not known whether intravaginal Fenticonazole is excreted in breast milk. However, problems during lactation have not been documented, caution should be considered.
- Lomefent® are usually well tolerated .
- Some adverse reactions have rarely been reported including local irritation or sensitivity include mild burning sensation, erythema, and vaginal itching. (Should more persist irritation occur or resistant micro-organism develop, suspend the treatment and seek the doctor’s advice) .
- Due to Lomefent® poor absorption, no systemic effects should occur, provided the above instructions are carefully observed.
Lomefent® 1000 mg vaginal ovule :
-Trichomonas or mixed ( trichomonas and candida albicans ) vaginal infections :
- One 1000 mg ovule followed by a second administration 24 hours later, when necessary .
-Candida albicans infections :
- One 1000 mg ovule followed by a second administration in the evening . Should the symptoms persist, a second administration may be repeated after three days .
Lomefent® 600 mg vaginal ovule:
- One 600 mg ovule at bedtime followed by a second administration 3 days later if symptoms persist.
* The ovules must be introduced deep into the vagina and pushed well up to the fornix .
Lomefent® vaginal Cream :
- One applicator full (5 g) is administered into the vagina morning and before going to bed for three days.
- If local irritation and hypersensitivity reactions occur,treatment should be discontinued .
- General hygienic measures should be observed to control sources of infection or reinfection.
- Appropriate therapy is indicated when the sexual partner is also infected .
- Lomefent® 600 mg ovule: Pack of one ovule.
- Lomefent® 1000 mg ovule: Pack of one ovule.
- Lomefent® Vaginal cream: Tube of 30 g with applicator
- Store in a dry place away from light at a temperature below 30 0C .