Acyclo® cream
  • Acyclo® cream preparation contains Acyclovir as an antiviral agent which is highly active against herpes simplex virus (HSV) types I, II and varicella zoster virus.
  • Phosphorylation of Acyclovir occurs after entry into herpes infected cells to the active compound  Acyclovir triphosphate, this being dependent on the presence of viral coded thymidine kinase.
  • Acyclovir triphosphate acts as herpes specified DNA polymerase inhibitor, preventing further viral DNA synthesis without affecting normal cells of human.

Acyclo® cream contains: 

  • Acyclovir             5% .
  • Acyclo® cream is indicated for the treatment of herpes simplex infections including initial and recurrent genital herpes and herpes labials.
  • Acyclo® cream is contraindicatied in patients with known hypersensitivity to acyclovir. 
  • Studies do not demonstrate any effects for acyclovir on embryos of animals. It is not known if topically applied Acyclovir is excreted in breast milk despite the lack of systemic exposure after topical administration.
  • Mothers who suffer from the presence of Herbsah lesions (herpes) on breasts or near them must avoid breast-feeding while applying the medicine on it.
  • Transient stinging or burning after application of Acyclo® cream may occur in some patients;occasionally erythema, itching or drying of the skin.    
  • Acyclo® cream should be applied five times daily at approximately 4-hourly intervals omitting the night time dose.
  • Acyclo® cream should be applied to the lesions or impending lesions as early as possible after starting of an infection. It is particularly important to start treatment of recurrent episodes during the prodromal period or when the lesions appear.
  • Treatment should be continued for 5 days.
  • Acyclo® cream is not recommended for application on the eye or to mucous, e.g , mouth or vagina, particular care should be taken to avoid accidental introduction into the eye. 
  • Tube of Acyclo® cream contains 15 g.
  • Store at temperature below 25º C.